The USP30 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Mouse, Rat, Canine, and Non-Human Primate antigen. The USP30 Antibody has been validated for the following applications: Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
USP30 is a deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PARK2): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin's ability to drive mitophagy